Purpose
This study aimed to develop and examine the effects of a mobile application-based self-management program for Chemotherapy-Induced Peripheral Neuropathy (CIPN) in colorectal cancer patients.
Methods
This study used a nonequivalent control group and a pretest-posttest design. Eighty-three patients with colorectal cancer undergoing neurotoxic chemotherapy were included in the study (experimental group, n=41; control group, n=42). The self-management program for CIPN consisted of an eight-week program (for individual training and telephonic coaching). CIPN 20, a CIPN assessment tool, and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30 scale were used to assess CIPN, disturbance of activities of daily living, and quality of life, respectively. The study was conducted from December 7, 2018, to August 20, 2019. For data analysis, descriptive statistics, a test of homogeneity in the pretest, independent t-tests, and repeated-measures analysis of variance were used.
Results
In the experimental group, significant improvements were found in CIPN (F=5.88, p=.018) and disturbance of activities of daily living (F=8.26, p=.005) compared to those in the control group. There was no significant difference in the interaction between the groups and time in terms of quality of life.
Conclusion
Our results indicate that the mobile application-based self-management program used in this study is effective and could be used as a nursing intervention for cancer patients with CIPN.

Purpose
This study was conducted to verify the effects of foot bathing on peripheral neuropathy, sleep disorder, and fatigue in gynecologic patients with cancer undergoing chemotherapy. Methods: There were 30 participants in this study who had been diagnosed with gynecologic cancer and were undergoing chemotherapy. Among them, 15 were in the experimental group of the K university hospital and 15 in the control group of the other K university hospital in D city. The experimental group received foot bathing once a day for 30 minutes over 10 days, an hour before bedtime, while the control group did not receive any foot bathing. Results: The results of the study showed that the experimental group that received foot bathing had significant changes in objective peripheral neuropathy (p=.021), sleep disorder (p=.002), and fatigue (p=.030), as compared to the control group. However, no significant difference was found between the experimental and the control groups regarding subjective peripheral neuropathy (p=.256). Conclusion: Hence, our study confirmed that foot bathing can be an effective nursing intervention to reduce peripheral neuropathy, sleep disorder, and fatigue in gynecologic patients with cancer undergoing chemotherapy.

Citations

• The impact of peripheral neuropathy symptoms, self-care ability, and disturbances to daily life on quality of life among gynecological cancer patients undergoing chemotherapy: a cross-sectional survey
  Sohee Mun, Hyojung Park
  Korean Journal of Women Health Nursing.2022; 28(4): 296.     CrossRef

Purpose
This review aimed to evaluate the effectiveness of exercise on Chemotherapy-induced Peripheral Neuropathy (CIPN).
Methods
The medical databases PubMed, EMBASE, and CINAHL, and several Korean databases were searched until December 2020. Additionally, a manual search was conducted. The risk of bias was assessed using the revised Cochrane risk-of-bias tool for randomized trials. The Review Manager 5.3 version of the Cochrane Library was used to estimate effect size through meta-analysis.
Results
Nine studies were included. The most common types of exercise reported were yoga, combined aerobics and strength exercise, and combined strength and balance exercise; each was backed by two studies. Four randomized controlled trials were meta-analyzed, and five studies were synthesized qualitatively. A significant effect on CIPN was found using meta-analysis (standardized mean difference=-0.28, 95% confidence interval=-0.47~-0.09, p=.004). As a result of qualitative synthesis, groups that did exercises were reported to have significantly lessened CIPN symptoms than control groups in three studies. In one study, the exercise group showed significant reduction in CIPN symptoms. And in another, the exercise group was more relieved of CIPN symptoms than the control group, although the difference was not significant.
Conclusion
The results indicate that exercise should be part of the regimen for patients who are receiving or have completed neurotoxic chemotherapy, for relieving CIPN symptoms. However, these results should be interpreted cautiously, especially due to the limited number of studies and the small number of participants. Therefore, further well-designed studies with sufficient numbers of participants are required.

Citations

• Factors Associated with Quality of Life in Cancer Patients Experiencing Chemotherapy-Induced Peripheral Neuropathy (CIPN) : Scoping review
  Minah Cho, Injung Hyun, Jiyeon Lee
  Asian Oncology Nursing.2025; 25(2): 75.     CrossRef
• The impact of peripheral neuropathy symptoms, self-care ability, and disturbances to daily life on quality of life among gynecological cancer patients undergoing chemotherapy: a cross-sectional survey
  Sohee Mun, Hyojung Park
  Korean Journal of Women Health Nursing.2022; 28(4): 296.     CrossRef