Purpose
This study aimed to develop and examine the effects of a mobile application-based self-management program for Chemotherapy-Induced Peripheral Neuropathy (CIPN) in colorectal cancer patients.
Methods
This study used a nonequivalent control group and a pretest-posttest design. Eighty-three patients with colorectal cancer undergoing neurotoxic chemotherapy were included in the study (experimental group, n=41; control group, n=42). The self-management program for CIPN consisted of an eight-week program (for individual training and telephonic coaching). CIPN 20, a CIPN assessment tool, and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30 scale were used to assess CIPN, disturbance of activities of daily living, and quality of life, respectively. The study was conducted from December 7, 2018, to August 20, 2019. For data analysis, descriptive statistics, a test of homogeneity in the pretest, independent t-tests, and repeated-measures analysis of variance were used.
Results
In the experimental group, significant improvements were found in CIPN (F=5.88, p=.018) and disturbance of activities of daily living (F=8.26, p=.005) compared to those in the control group. There was no significant difference in the interaction between the groups and time in terms of quality of life.
Conclusion
Our results indicate that the mobile application-based self-management program used in this study is effective and could be used as a nursing intervention for cancer patients with CIPN.

Purpose
This review aimed to evaluate the effectiveness of exercise on Chemotherapy-induced Peripheral Neuropathy (CIPN).
Methods
The medical databases PubMed, EMBASE, and CINAHL, and several Korean databases were searched until December 2020. Additionally, a manual search was conducted. The risk of bias was assessed using the revised Cochrane risk-of-bias tool for randomized trials. The Review Manager 5.3 version of the Cochrane Library was used to estimate effect size through meta-analysis.
Results
Nine studies were included. The most common types of exercise reported were yoga, combined aerobics and strength exercise, and combined strength and balance exercise; each was backed by two studies. Four randomized controlled trials were meta-analyzed, and five studies were synthesized qualitatively. A significant effect on CIPN was found using meta-analysis (standardized mean difference=-0.28, 95% confidence interval=-0.47~-0.09, p=.004). As a result of qualitative synthesis, groups that did exercises were reported to have significantly lessened CIPN symptoms than control groups in three studies. In one study, the exercise group showed significant reduction in CIPN symptoms. And in another, the exercise group was more relieved of CIPN symptoms than the control group, although the difference was not significant.
Conclusion
The results indicate that exercise should be part of the regimen for patients who are receiving or have completed neurotoxic chemotherapy, for relieving CIPN symptoms. However, these results should be interpreted cautiously, especially due to the limited number of studies and the small number of participants. Therefore, further well-designed studies with sufficient numbers of participants are required.

Citations

• Factors Associated with Quality of Life in Cancer Patients Experiencing Chemotherapy-Induced Peripheral Neuropathy (CIPN) : Scoping review
  Minah Cho, Injung Hyun, Jiyeon Lee
  Asian Oncology Nursing.2025; 25(2): 75.     CrossRef
• The impact of peripheral neuropathy symptoms, self-care ability, and disturbances to daily life on quality of life among gynecological cancer patients undergoing chemotherapy: a cross-sectional survey
  Sohee Mun, Hyojung Park
  Korean Journal of Women Health Nursing.2022; 28(4): 296.     CrossRef

PURPOSE
The purpose of this study was to investigate resilience and its mediating effect on the association between symptom distress and depression among recurrent gynecologic cancer patients undergoing chemotherapy.
METHODS
A purposive sample of 113 patients diagnosed with recurrent gynecologic cancer was recruited. A cross-sectional survey design was used. The data were collected through a structured questionnaire from September to November 2014.
RESULTS
There was a positive correlation between symptom distress and depression. Negative correlational relationships were found between symptom distress and resilience and between resilience and depression. Resilience showed a partial mediating effect between symptom distress and depression (Z=2.34, p=.019).
CONCLUSION
The results suggest that the negative effects of symptom distress on depression can be reduced by improving the resilience. Further, it is necessary to explore the multidimensional constructs of resilience and develop intervention programs that can improve the resilience among recurrent gynecologic cancer patients.

Citations

• Mediating Effect of Resilience between Supportive Care Needs and Quality of Life of Female Genital Cancer Patients
  Yu-Jung Son, Keum-Hee Nam
  Korean Journal of Adult Nursing.2022; 34(3): 269.     CrossRef
• Symptoms, resilience, coping, and psychosocial adjustment in women with gynaecological cancer in South Korea: A cross sectional study
  Sun Young Yu, Ju-Hee Nho, Mi Hyun Jung, Hyun Yi Kim, Hyun Jin An, Hyun Ah Choi
  European Journal of Oncology Nursing.2022; 56: 102097.     CrossRef

PURPOSE
Sleep disturbances related to multiple conditions are common in patients with cancer while undergoing chemotherapy. The quality of life in these patients may be negatively affected due to sleep disturbances. Therefore, by analyzing nursing records, this study aimed to examine factors influencing sleep disturbances among hospitalized patients with colorectal cancer undergoing chemotherapy.
METHODS
This study was a retrospective review of nursing records of 231 patients with colorectal cancer who were hospitalized for chemotherapy in 2015. Data were collected from electronic medical records, and analyzed using the independent t-test, χ2 test, and logistic regression.
RESULTS
Thirty-five (15.2%) patients had sleep disturbances. Nursing records related to sleep (n=85) consisted of 32 (37.6%) assessments and 53 (62.4%) interventions. Pharmacological interventions for sleep disturbances (98.1%) were used more often as compared to non-pharmacological interventions (1.9%). In logistic regression analysis, sleep disturbances were related to the body mass index (Odds Ratio [OR]=0.86, 95% Confidence Interval [CI]=0.76~0.98), targeted therapy(OR=2.62, 95% CI=1.09~6.32), and length of hospital stay (OR=1.08, 95% CI=1.02~1.14).
CONCLUSION
Sleep disturbances were influenced by body mass index, targeted therapy, and length of hospital stay. Thus, nutritional and psycho-emotional status after metastasis or recurrence should be closely monitored in patients with colorectal cancer undergoing chemotherapy, especially during prolonged hospitalization. Further, in addition to the use of pharmacological interventions, various non-pharmacological nursing interventions to promote sleep health should be developed.

Citations

• Effect of Healing Beats Program on Stress, Heart Rate and Sleep Quality of Colorectal Cancer Patients Treated with Chemotherapy: A Randomized Controlled Trial
  Eun-Jeong Hong
  Asian Oncology Nursing.2024; 24(1): 32.     CrossRef
• The Effect of a Supportive Educational Intervention Through Virtual Social Networks on Sleep Quality and Insomnia of Patients with Cancer
  Elahe Sarlak, Jamshid Ansari, Rahmatollah Moradzadeh, Nazi Nejat
  Journal of Cancer Education.2023; 38(5): 1675.     CrossRef
• Systematic Review of the Pittsburgh Sleep Quality Index used for Measuring Sleep Quality among Adults with Trauma Experiences
  Go-Un Kim, Ju Hee Lee
  Korean Journal of Adult Nursing.2019; 31(4): 337.     CrossRef