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"Adherence"

Original Articles
Factors related to Medication Adherence in Patients with Heart Failure
Nina So, Hyunli Kim
Korean J Adult Nurs 2021;33(3):203-211.   Published online June 30, 2021
DOI: https://doi.org/10.7475/kjan.2021.33.3.203
Purpose
The purpose of this study was to determine the levels of medication adherence in patients with heart failure and explore the factors related to it.
Methods
Cross-sectional and descriptive surveys were conducted in 107 patients with heart failure who visited C Hospital in D City. Data were collected from patients using self-report questionnaires between May 2015 and November 2016, and their medical records were identified. Data were analyzed using independent t-test, one-way ANOVA, and correlation and hierarchical multiple regression analyses using SPSS.
Results
The mean score of medication adherence was 10.23±2.70. Patients with long-term adverse effects showed worse medication adherence than those without long-term adverse effects (t=2.55, p=.012). Medication adherence positively correlated with depression (r=.34, p=.001) and barriers (r=.48, p=.001) but negatively correlated with attitude (r=-.39, p=.001). The hierarchical multiple regression analysis showed that the model with two independent variables of long-term adverse effects (β=-.23, p=.008) and barriers (β=.37, p<.001) explained the 29.6% in medication adherence (F=11.93, p<.001).
Conclusion
To improve medication adherence, a nursing strategy to reduce long-term adverse effects and barriers accompanied by continuous monitoring is required.

Citations

Citations to this article as recorded by  
  • A predictive model for medication adherence in older adults with heart failure
    Eun Ha Oh, Chun-Ja Kim, Elizabeth A Schlenk
    European Journal of Cardiovascular Nursing.2024; 23(6): 635.     CrossRef
  • One‐year trajectories of self‐care behaviours and unplanned hospital readmissions among patients with heart failure: A prospective longitudinal study
    Youn‐Jung Son, Insil Jang
    Journal of Clinical Nursing.2023; 32(17-18): 6427.     CrossRef
  • The Role of Depression on Treatment Adherence in Patients with Heart Failure–a Systematic Review of the Literature
    Valentina Poletti, Francesco Pagnini, Paolo Banfi, Eleonora Volpato
    Current Cardiology Reports.2022; 24(12): 1995.     CrossRef
  • 230 View
  • 24 Download
  • 3 Crossref
  • 3 Scopus
Factors Associated with Medication Adherence among the Elderly with Chronic Diseases
Sook Hee Kang, Eun Ko
Korean J Adult Nurs 2021;33(2):189-201.   Published online April 30, 2021
DOI: https://doi.org/10.7475/kjan.2021.33.2.189
Purpose
The study sought to investigate the relationships between beliefs about medications, self-efficacy of medication use, social support and medication adherence, and the general factors associated with medication adherence among the elderly living with chronic disease. Methods: This study took the form of a descriptive survey involving 222 elderly outpatients - aged 65 years or older - who visited S medical center, located in S city. Data were collected through self-report questionnaires from July to August 2019. Data analysis was conducted using descriptive statistics, an independent t-test, a one-way ANOVA, Pearson's correlation coefficient, and a hierarchical multiple regression via the SPSS/WIN 25.0 program. Results: The mean score for medication adherence was 61.80±10.19 (range 16~80). Participants' medication adherence positively correlated with beliefs about medications (r=.17, p=.012), self-efficacy for medication use (r=.31, p<.001) and social support (r=.20, p=.003). Frequency of alcohol consumption (β=-.20, p=.001), burden level of medical costs (β=-.18, p=.012), experience of side-effects (β=-.21, p=.001), medication-taking education (β=.17, p=.008), beliefs about medication (β=.13, p=.038), and self-efficacy for medication use (β=.19, p=.004) explained for 24.9% of medication adherence (F=6.23, p<.001). Conclusion: It is necessary to consider the beliefs about medication and self-efficacy for medication use when developing educational programs aimed at improving medication adherence among the elderly living with chronic diseases.

Citations

Citations to this article as recorded by  
  • Factors associated with health literacy in older adults aged 65 and over: a secondary data analysis of the 2021 Korea Health Panel applying the Andersen behavioural model
    Yeong Eun Kim, Ol Han, Chang Sun Moon
    BMJ Open.2025; 15(3): e085696.     CrossRef
  • Factors Influencing Medication Adherence among Adult Patients with Hypertension
    Soo Kyung Lee, Myung Sun Hyun
    The Korean Journal of Rehabilitation Nursing.2025; 28(1): 1.     CrossRef
  • Factors associated with medication adherence among older adults with multimorbidity: A culture perspective
    Eunhwa Lee, MoonKi Choi
    Geriatric Nursing.2024; 55: 297.     CrossRef
  • Factors Influencing the Medication Adherence in Patients with Pulmonary Tuberculosis in the COVID-19 Pandemic
    Bongsil Lim, Min Young Kim
    The Korean Journal of Rehabilitation Nursing.2023; 26(2): 87.     CrossRef
  • Development and effectiveness of an integrated medication management program centered on senior welfare centers for older adults with hypertension: A cross-sectional study
    Heuijeong Moon, Dukyoo Jung
    Journal of Korean Gerontological Nursing.2023; 25(3): 297.     CrossRef
  • Relationships between health literacy, self-efficacy, and medication adherence in older people with polypharmacy: A cross-sectional study
    Jee Young Cho, Sun Ju Chang
    Journal of Korean Gerontological Nursing.2023; 25(4): 357.     CrossRef
  • Effects of Changes in Multiple Chronic Conditions on Medical Costs among Older Adults in South Korea
    Soojin Park, Jin Young Nam
    Healthcare.2022; 10(4): 742.     CrossRef
  • 488 View
  • 27 Download
  • 7 Crossref
  • 5 Scopus
Effects of a Medication Adherence Promotion Program in Breast Cancer Patients under Adjuvant Hormonal Therapy
Seung Hee Yu, Jeong Hee Kang
Korean J Adult Nurs 2020;32(3):223-234.   Published online June 30, 2020
DOI: https://doi.org/10.7475/kjan.2020.32.3.223
Purpose
The objective of this study was to assess effects of a medication adherence promotion program for breast cancer patients receiving adjuvant hormonal therapy.
Methods
This study used a randomized control group repeated measures design. A total of 79 participants were recruited from an outpatient clinic in the Chonbuk National University Hospital, Jeonju city. The program's effects on medication adherence, perceived stress, depression, and fatigue were assessed at three points: before, at the 9th week, and again at the 16th week of the program application. The data were collected from July 3 to November 9, 2017.
Results
Statistically significant differences in changes in medication adherence, perceived stress, and depression over the assessment points between experimental and control groups were revealed. Scores on medication adherence in the experimental group improved at the 9th week mark and lowered a little at the 16th week, but remained higher than before the program application, however. Scores on perceived stress and depression in the experimental group improved at the 9th week and stayed almost at the same level at the 16th week.
Conclusion
It is clear that consistent nursing interventions are needed to promote and maintain medication adherence and associated symptoms, particularly for breast cancer patients who require long-term hormonal therapy.
  • 125 View
  • 1 Download
  • 1 Scopus
PURPOSE
This study was conducted to identify factors associated with oncology nurses' adherence to Chemotherapy-Induced Neutropenia (CIN) guidelines based on Pender's Health Promotion Model (HPM).
METHODS
For this cross-sectional descriptive study, 187 nurses who worked at the oncology department of Channam National University Hawsun Hospital responded to self-administered questionnaires. A tool for CIN guideline adherence was developed through systematic search, synthesis, translation, and content validation. Data collection was conducted by a trained research assistant from September 18 to September 26, 2017. Data were analyzed using independent t-test, one-way ANOVA, Pearson's correlation coefficient, and stepwise multiple regression.
RESULTS
Stepwise multiple regression showed that guideline adherence was associated with CIN education (β=.26, p<.001), self-efficacy (β=.17, p=.018), perceived benefits (β=.16, p=.026), interpersonal factors (β=.16, p=.043), and educational level (β=.14, p=.030).
CONCLUSION
The findings of this study could be used to develop interventions focusing on CIN education and for the strengthening oncology nurses' self-efficacy and beliefs to promote adherence to CIN guidelines. In addition, repeated studies would be needed to verify application of Pender's HPM to explain nurses' adherence.
  • 143 View
  • 1 Download
  • 0 Scopus
Predictors Influencing of Medication Adherence in Hemodialysis Patients
Hana Kim, Eunha Kim
Korean J Adult Nurs 2019;31(3):283-292.   Published online June 30, 2019
DOI: https://doi.org/10.7475/kjan.2019.31.3.283
PURPOSE
The aim of this study was to investigate factors affecting medication adherence in hemodialysis patients.
METHODS
A convenience sample of 140 patients receiving hemodialysis was selected. Data were collected from December. 1. 2016 to January. 15. 2017 using a self-reported questionnaires including the eight-item Morisky's Medication Adherence Scale Korean version (K-MMAS-8). The collected data were analyzed with a descriptive test, independent t-test, one-way ANOVA, Pearson's correlation coefficient and stepwise multiple regression with SPSS/WIN 23.0.
RESULTS
The patients showed a low level of medication adherence (M±SD=5.75±1.65). There were significant differences in medication adherence according to subjective health status (F=6.88, p=.001) and discomfort in taking medication (t=−4.59, p<.001). Expectation of medication (r=.42, p<.001) and disgust of medication (r=−.36, p<.001) were the significant factors related to medication adherence. It was explained by expectation of medication (β=.30, p<001), disgust of medication (β=−.21, p=.007), discomfort in taking medication (β=.20, p=.010) and subjective health status (β=−.18, p=.016).
CONCLUSION
It is necessary not only to regularly monitor patients' medication behavior but also develop and implement an individualized nursing intervention that reflects expectation and disgust of medication.

Citations

Citations to this article as recorded by  
  • Effect of depression and empowerment on medication adherence in patients with breast cancer: a descriptive survey
    Sookyung Jeong, Eun Jeong Kim
    BMC Nursing.2025;[Epub]     CrossRef
  • Factors Influencing Medication Adherence in Patients Undergoing Hemodialysis
    Jeonghyeon Kim, Jieun Cha
    Journal of Korean Academy of Fundamentals of Nursing.2024; 31(1): 18.     CrossRef
  • Factors Affecting Hyperphosphatemia in Patients with Chronic Renal Failure Undergoing Hemodialysis
    Jihyun Kim
    Journal of Korean Academy of Fundamentals of Nursing.2023; 30(2): 247.     CrossRef
  • A study of relationships among tuberculosis knowledge, family support, and medication adherence in tuberculosis patients
    Yoo-Ri Jang, Mi-Aie Lee
    The Journal of Korean Academic Society of Nursing Education.2022; 28(1): 80.     CrossRef
  • Factors Associated with Medication Adherence among the Elderly with Chronic Diseases
    Sook Hee Kang, Eun Ko
    Korean Journal of Adult Nursing.2021; 33(2): 189.     CrossRef
  • Factors Influencing Self-Care Behavior and Treatment Adherence in Hemodialysis Patients
    Hana Kim, Mi-Kyoung Cho
    International Journal of Environmental Research and Public Health.2021; 18(24): 12934.     CrossRef
  • Effects of a Medication Adherence Promotion Program in Breast Cancer Patients under Adjuvant Hormonal Therapy
    Seung Hee Yu, Jeong Hee Kang
    Korean Journal of Adult Nursing.2020; 32(3): 223.     CrossRef
  • 151 View
  • 3 Download
  • 7 Crossref
  • 8 Scopus
Factors Related to Medication Adherence in Adult Patients with Tuberculosis
Eun Young Jung, Sun Kyung Hwang
Korean J Adult Nurs 2018;30(5):493-503.   Published online October 31, 2018
DOI: https://doi.org/10.7475/kjan.2018.30.5.493
PURPOSE
This study aimed to explore medication adherence and its related factors, stigma, self-efficacy, and sense of coherence in patients with tuberculosis.
METHODS
A cross-sectional survey was conducted with a convenience sample of 130 adult outpatients with tuberculosis at a university hospital in Busan during from May 1 to August 21, 2017. The data were collected using structured questionnaires comprising research instruments measuring medication adherence, stigma, self-efficacy, and sense of coherence and face-to-face interviews and medical records for treatment delays and participant characteristics. The SPSS/WIN 22.0 program for descriptive statistics, Pearson's correlation coefficients and stepwise multiple regression were used to analyze the data.
RESULTS
The mean score for medication adherence was 4.86±1.48. The factors related to medication adherence in adult outpatients with tuberculosis were stigma (β=−.23, p=.004), self-efficacy (β=.20, p=.036), perceived family support (β=.19, p=.012), and alcohol (β=−.19, p=.021), which explained 38.9% of the variance in medication adherence.
CONCLUSION
The study results suggest that a nursing intervention must be designed to reduce stigma, improve self-efficacy, promote family support, and stop alcohol consumption in order to enhance the medication adherence in adult patients with tuberculosis. Efforts need to educate and encourage tuberculosis patients to adhere strictly to their drugs and conduct various campaigns against the negative perception of tuberculosis.

Citations

Citations to this article as recorded by  
  • Factors Influencing the Medication Adherence in Patients with Pulmonary Tuberculosis in the COVID-19 Pandemic
    Bongsil Lim, Min Young Kim
    The Korean Journal of Rehabilitation Nursing.2023; 26(2): 87.     CrossRef
  • Health-Related Quality of Life Based on EQ-5D Utility Score in Patients With Tuberculosis: A Systematic Review
    Hae-Young Park, Hyo-Bin Cheon, Sun Ha Choi, Jin-Won Kwon
    Frontiers in Pharmacology.2021;[Epub]     CrossRef
  • Factors Associated with Medication Adherence among the Elderly with Chronic Diseases
    Sook Hee Kang, Eun Ko
    Korean Journal of Adult Nursing.2021; 33(2): 189.     CrossRef
  • THE EFFECT VIDEO MEDIA PSYCHEDUCATION ON ANXIETY LEVELS AND SELF EFFICACY OF TUBERCULOSIS PATIENTS IN THE TREATMENT AT PARU CENTER RSUD CILACAP
    Rosi Arista
    Critical Medical and Surgical Nursing Journal.2020; 9(1): 34.     CrossRef
  • 135 View
  • 1 Download
  • 4 Crossref
  • 4 Scopus
Factors Affecting Adherence to Self-care Behaviors among Outpatients with Heart Failure in Korea
Jong Sun Ok, Heejung Choi
Korean J Adult Nurs 2015;27(2):242-250.   Published online April 30, 2015
DOI: https://doi.org/10.7475/kjan.2015.27.2.242
PURPOSE
To evaluate heart failure knowledge and adherence to self-care behaviors, and to identify factors affecting adherence to self-care behaviors among Korean patients with heart failure.
METHODS
Correlational research using the European Heart Failure Self-care Behavior Scale, the Duke Activity Status Index, the Dutch Heart Failure Knowledge Scale, the New York Heart Association Functional Classification, and the Medical Outcomes Study Social Support Survey was conducted. A total of 280 outpatients with heart failure responded to the five questionnaires.
RESULTS
The mean scores for self-care adherence and heart failure knowledge were 31.98 +/- 6.81 and 8.78 +/- 2.53, respectively, indicating lower adherence and knowledge than those previously reported. Subjects with lower functional status, more social supports, and greater knowledge of heart failure are more likely to adhere to prescribed regimens.
CONCLUSION
Nurses should focus on patient education and support to improve their adherence to self-care behaviors.

Citations

Citations to this article as recorded by  
  • Levels of adherence to treatment, illness perception and acceptance of illness in patients with coronary artery disease - descriptive and correlational study
    Farzad Dugunchi, Shiv Kumar Mudgal, Zohreh Hosseini Marznaki, Hoda Shirafkan, Saeed Abrotan, Fateme Jafarian, Roghayeh Pourkia
    BMC Cardiovascular Disorders.2024;[Epub]     CrossRef
  • Self-care behavior and associated factors among adult heart failure patients in outpatient cardiac follow-up unit at Wachemo University Nigist Eleni Comprehensive Specialized Hospital, Southern Ethiopia
    Ermias Sigebo Sugebo, Teshager Worku Kassie, Tesfaye Gobena, Temesgen Kechine Tibore, Sisay Foga Sebro, Tadesse Lelago Ermolo
    BMC Cardiovascular Disorders.2024;[Epub]     CrossRef
  • Individual and systems-related factors associated with heart failure self-care: a systematic review
    Carolyn Kleman, Stephanie Turrise, Heidi Winslow, Omar Alzaghari, Barbara J. Lutz
    BMC Nursing.2024;[Epub]     CrossRef
  • Adherence to self-care practices and associated factors among heart failure patients in Ethiopia: A systematic review and meta-analysis
    Firomsa Bekele, Lalise Tafese, Addisalem Workie Demsash, Hana Tesfaye, Busha Gamachu Labata, Ginenus Fekadu, Mohammed Feyisso Shaka
    PLOS ONE.2023; 18(8): e0288824.     CrossRef
  • Self-Care and Quality of Life Among Adult Patients With Heart Failure: Scoping Review
    Sheka Shemsi Seid, José Amendoeira, Maria Regina Ferreira
    SAGE Open Nursing.2023;[Epub]     CrossRef
  • Psychosocial Interventions to Enhance Treatment Adherence to Lifestyle Changes in Cardiovascular Disease: A Review of the Literature 2011-2021
    Aspasia Pizga, Eleftherios Karatzanos, Stamatoula Tsikrika, Vassiliki Gioni, Ioannis Vasileiadis, Serafim Nanas, Panagiotis Kordoutis
    European Journal of Environment and Public Health.2022; 6(1): em0102.     CrossRef
  • Validity and Reliability of the Korean Version of the Revised Self-Care of Heart Failure Index v7.2
    JinShil Kim, Kye Hun Kim, Young-Hyo Lim, Seongkum Heo, Keumyi Moon, Mi Sook Oh, Minjeong An
    Clinical Nursing Research.2022; 31(7): 1296.     CrossRef
  • The Relationship Between Body Awareness and Self-care in Patients With Heart Failure
    Kyoung Suk Lee, Jin-Oh Choi, Eun-Seok Jeon, Jae-Hyeong Park, Mi Sook Jung
    Journal of Cardiovascular Nursing.2022; 37(3): 266.     CrossRef
  • Adherence to Self-Care Recommendations and Associated Factors among Adult Heart Failure Patients in West Gojjam Zone Public Hospitals, Northwest Ethiopia
    Belayneh Molla, Haimanot Abebe Geletie, Girma Alem, Tenaw Gualu, Bitew Tefera Zewudie, Shegaw Tesfa, Tadesse Tsehay, Baye Tsegaye Amlak, Khoa Nguyen
    International Journal of Chronic Diseases.2022; 2022: 1.     CrossRef
  • Developing a Middle-Range Theory of Heart Failure Self-Care
    Sumayya A. Attaallah, Rosalind M. Peters, Ramona Benkert, Hossein Yarandi, Sandra Oliver-McNeil, Faith Hopp
    Nursing Science Quarterly.2021; 34(2): 168.     CrossRef
  • Self-Care Behavior and Associated Factors among Heart Failure Patients in Tigray, Ethiopia: A Cross-Sectional Study
    Tsegu Hailu Gebru, Kalayou Kidanu Berhe, Weyzer Tilahun Tsehaye, Haftea Hagos Mekonen, Kbrom Gemechu Kiros, Tesfay Gebreslassie Gebrehiwot, Gessessew Teklebrhan Gebrehiwot, Yared Hailesilassie Teka, Hayat Maeruf Mohammed
    Clinical Nursing Research.2021; 30(5): 636.     CrossRef
  • Knowledge, Adherence to Lifestyle Recommendations, and Quality of Life Among Koreans With Heart Failure
    Haejung Lee, Gaeun Park, Kyoung Suk Lee, HyeKyung Jin, Kook-Jin Chun, Jong Hyun Kim
    Journal of Cardiovascular Pharmacology and Therapeutics.2020; 25(4): 324.     CrossRef
  • Adherence to self-care recommendations and associated factors among adult heart failure patients. From the patients’ point of view
    Mohammed Assen Seid, Ousman Abubeker Abdela, Ejigu Gebeye Zeleke, Amir H. Pakpour
    PLOS ONE.2019; 14(2): e0211768.     CrossRef
  • Distinct Factors Associated With Better Self-care in Heart Failure Patients With and Without Mild Cognitive Impairment
    Kyoung Suk Lee, Jin-Oh Choi, Eun-Seok Jeon, Jae-Hyeong Park, Mi Sook Jung, Zian Lee, Hyeong Suk Lee, Hye Jin Yoo
    Journal of Cardiovascular Nursing.2019; 34(6): 440.     CrossRef
  • Factors related to self-care behaviours in heart failure: A systematic review of European Heart Failure Self-Care Behaviour Scale studies
    Natasa Sedlar, Mitja Lainscak, Jan Mårtensson, Anna Strömberg, Tiny Jaarsma, Jerneja Farkas
    European Journal of Cardiovascular Nursing.2017; 16(4): 272.     CrossRef
  • 116 View
  • 2 Download
  • 15 Crossref
Factors Influencing Adherence to Vestibular Rehabilitation Exercise Program in Patients with Dizziness
Hyun Jung Lee, Smi Choi-Kwon
Korean J Adult Nurs 2014;26(4):434-443.   Published online August 31, 2014
DOI: https://doi.org/10.7475/kjan.2014.26.4.434
PURPOSE
This study investigated the level of adherence to vestibular rehabilitation exercise program(VREP) and evaluated how health belief model (HBM) variables are related with adherence to VREP in patients with dizziness.
METHODS
The data were collected from 150 individuals, who agreed to participate in the study between December, 2012 and May, 2013. Adherence to VREP, severity of dizziness, health belief variables (health belief scale) and self-efficacy (self-efficacy scale) were measured.
RESULTS
The result of this study showed poor adherence to VREP. The mean adherence score to VREP was 2.11+/-1.05 (1-5). In multivariate analysis, severity of dizziness (p<.001), taking sedative medication (p<.001), high self-efficacy (p<.001), high perceived seriousness (p=.019) & benefit (p=.036) were independent predicting factors explaining 57.7% of adherence to VREP.
CONCLUSION
Adherence to VREP was poor among these patients. To improve the patient's adherence to VREP, strategies to increase perceived seriousness, benefit, or self-efficacy and to decrease barriers are urgently needed.

Citations

Citations to this article as recorded by  
  • Barriers and Facilitators of Vestibular Rehabilitation: Patients and Physiotherapists’ Perspectives
    Liran Kalderon, Azriel Kaplan, Amit Wolfovitz, Shelly Levy-Tzedek*, Yoav Gimmon*
    Journal of Neurologic Physical Therapy.2024; 48(3): 140.     CrossRef
  • Review on Physical Therapy for Patients with Vestibular Disorder
    Yong Hyun Kwon, Yu Min Ko
    The Journal of Korean Physical Therapy.2017; 29(6): 316.     CrossRef
  • Effectiveness of Self-efficacy Promoting Vestibular Rehabilitation Program for Patients with Vestibular Hypofunction
    Hyun Jung Lee, Smi Choi-Kwon
    Journal of Korean Academy of Nursing.2016; 46(5): 710.     CrossRef
  • 99 View
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  • 3 Crossref
An Explanatory Model for Patient Adherence of Rehabilitation in patients with Spinal Cord Injury
Aee Lee Kim
J Korean Acad Adult Nurs 2010;22(1):90-102.   Published online February 28, 2010
PURPOSE
The purpose of this study was to identity factors affecting patient adherence and to develop an explanatory model for patient adherence in patients with spinal cord injury. 8 variables that were based on the previous research and a review of literature were used to construct hypothetical model. Social support, economic status, perceived barrier, patient provider relationship and rehabilitation related knowledge were the exogenous variables, depression, self-efficacy and patient adherence were the endogenous variables.
METHODS
Data form 117 patients with SCI were analysed to test the hypothetical model, using SAS and LISREL 8.53 program.
RESULTS
The overall fitness of the model was good (GFI=.991, AGFI=.915, NNFI=1.299, NFI=.953, p=.632) Depression, powerlessness, economic status were the strong factors influencing patient adherence. Powerlessness was significant factors for self-efficacy.
CONCLUSION
To improve of patient adherence should focus on nursing intervention for depression, powerlessness and economic status.
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