Purpose
This review aimed to evaluate the effectiveness of exercise on Chemotherapy-induced Peripheral Neuropathy (CIPN).
Methods
The medical databases PubMed, EMBASE, and CINAHL, and several Korean databases were searched until December 2020. Additionally, a manual search was conducted. The risk of bias was assessed using the revised Cochrane risk-of-bias tool for randomized trials. The Review Manager 5.3 version of the Cochrane Library was used to estimate effect size through meta-analysis.
Results
Nine studies were included. The most common types of exercise reported were yoga, combined aerobics and strength exercise, and combined strength and balance exercise; each was backed by two studies. Four randomized controlled trials were meta-analyzed, and five studies were synthesized qualitatively. A significant effect on CIPN was found using meta-analysis (standardized mean difference=-0.28, 95% confidence interval=-0.47~-0.09, p=.004). As a result of qualitative synthesis, groups that did exercises were reported to have significantly lessened CIPN symptoms than control groups in three studies. In one study, the exercise group showed significant reduction in CIPN symptoms. And in another, the exercise group was more relieved of CIPN symptoms than the control group, although the difference was not significant.
Conclusion
The results indicate that exercise should be part of the regimen for patients who are receiving or have completed neurotoxic chemotherapy, for relieving CIPN symptoms. However, these results should be interpreted cautiously, especially due to the limited number of studies and the small number of participants. Therefore, further well-designed studies with sufficient numbers of participants are required.

Citations

• The impact of peripheral neuropathy symptoms, self-care ability, and disturbances to daily life on quality of life among gynecological cancer patients undergoing chemotherapy: a cross-sectional survey
  Sohee Mun, Hyojung Park
  Korean Journal of Women Health Nursing.2022; 28(4): 296.     CrossRef

Purpose
The purpose of this study was to assess the research performance during Coronavirus Disease 2019 (COVID-19) pandemic among nursing researchers. Methods: A cross-sectional online survey was conducted for Korean Society of Adult Nursing where 103 subjects participated from April 15 to May 14, 2021. The survey tool developed by researchers had 32 items including difficulties in performing research activities, perception of the impact of COVID-19 on research validity, and three open-ended questions. Results: In the research planning phase, 88 subjects (90.7%) reported difficulties in the recruitment plan and 83 subjects (89.3%) reported difficulties selecting a research design. In the recruitment and data collection phase, 85 subjects (88.6%) had difficulties accessing data collection site and 78 subjects (85.7%) had difficulties in face-to-face data collection. In the provision of intervention phase (for experimental study), 26 subjects (66.7%) reported that they should have changed the method of delivery of intervention. In research administration and manpower management, 62 subjects (75.6%) reported difficulties in face-to-face meeting. In research outcome management, 65 subjects (85.5%) reported that they should have changed the way of research-related events. Lastly, 80 subjects (81.6%) perceived that difficulties caused by COVID-19 impacted research validity. Conclusion: Majority of participants perceived that the difficulties in research activities may decrease research validity. To ensure research quality during COVID-19 pandemic, we should recognize potential threats to research validity and actively pursue adaptable innovations of research designs and data collection methods.