Purpose This study's purpose was to identify the relationship between daily vitamin intake and blood glucose in cancer patients undergoing chemotherapy and identify factors affecting blood glucose. Methods This descriptive study included 134 cancer patients undergoing chemotherapy at a university hospital. Data were analyzed with descriptive statistics, independent T-test, one-way analysis of variance, Pearson's correlation coefficients, and stepwise multiple regression analysis using SPSS/WIN 27.0 version. Results The average blood glucose of the subjects was 128.13±37.34 mg/dL and 30.6% of the subjects had readings of over 140 mg/dL. Blood glucose varied significantly by sex, age, education level, exercise frequency, and comorbidity. Vitamins A, E, and C, thiamin, riboflavin, niacin, vitamin B6, folate, and biotin were negatively correlated with blood glucose. Factors affecting blood glucose were exercising 7 times a week (β=-.61, p<.001), 4 to 6 times a week (β=-.41, p<.001), 1 to 3 times a week (β=-.38, p<.001), age (β=.18, p=.016), and vitamin A intake (β=-.16, p<.043), with a total explanatory power of approximately 31.5%. Conclusion Nurses should provide patients undergoing chemotherapy with lifestyle interventions including exercise at least 3 days a week and appropriate vitamin A intake, especially for older patients, to prevent hyperglycemia.
PURPOSE The purpose of this study was to evaluate the effect of antioxidant vitamins and magnesium supplementation on fasting blood glucose and lipids in patients with type 2 diabetes. METHODS This study is a unequivalent control group pretest-posttest design. Seventy-one subjects with type 2 diabetes who were recruited from home visiting clients of a public health center, completed the trial. The experimental group entered a 12-week treatment period with antioxidant vitamins and magnesium and the control group with no antioxidant vitamins and magnesium. RESULTS Serum level of fasting blood glucose decreased from 134.7 mg/dl to 125.0 mg/dl and total-cholesterol decreased from 215.5 mg/dl to 198.2 mg/dl in the experimental group. No changes in fasting blood glucose and total-cholesterol were demonstrated in the control group. CONCLUSIONS A short-term supplementation with antioxidant vitamins and magnesium can reduce fasting blood glucose and total-cholesterol in patients with type 2 diabetes. The continuous effect of this supplementation and the beneficial effect on the prevention of diabetes complication still needs to be demonstrated.