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"Transplantation"

Original Article

Risk Factors for Readmission of Heart Transplant Recipients: A Retrospective Case-Control Study
Da El Jang, Yeon Soo Jang
Korean J Adult Nurs 2024;36(1):52-62.   Published online February 29, 2024
DOI: https://doi.org/10.7475/kjan.2024.36.1.52
Purpose
The purpose of this study was to identify factors influencing the readmission of heart transplant recipients through survival analysis. Methods: We collected data from heart transplant recipients who were discharged after surgery between November 2005 and September 2020 from the electronic medical records of Y University Hospital in Seoul. The Kaplan-Meier estimation was utilized to calculate the survival rate, and Cox's proportional hazards model was employed to determine the factors influencing readmission within 1 year. Results: Out of 150 heart transplant recipients, 81 (54.0%) were readmitted within one year. The median time to readmission was 231 days. An increased duration of postoperative days was associated with a higher risk of readmission (p=.016). Groups with abnormal sodium levels (p<.001), those requiring postoperative hemodialysis (p=.013), patients with chronic kidney disease (p=.002), dyslipidemia (p=.040), or diabetes mellitus (p=.045) also faced higher readmission risks. In the final model, sodium levels (hazard ratio [HR]=2.31, p<.001) and chronic kidney disease (HR=1.67, p=.045) were significant risk factors for readmission (x2 =31.90, p<.001). Conclusion: Interventions to improve kidney function and a multidisciplinary approach are needed to reduce readmission of heart transplant recipients.
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Review Article

PURPOSE
This systematic review and meta-analysis provided scientific evidence for oral cryotherapy as a nursing intervention for the prevention of Oral Mucositis (OM) associated with Hematopoietic Stem Cell Transplantation (HSCT).
METHODS
The literature search was carried out in July and October 2017. The MEDLINE, EMBASE, Cochrane Library, CINAHL, and KoreaMed electronic databases were searched using the MeSH keywords “mucositis” and “cryotherapy.” The Cochrane's Risk of Bias tool was used to assess the internal validity of the Randomized Controlled Trials (RCTs). The selected studies were included in the meta-analysis using Review Manager 5.3.
RESULTS
Among seven RCTs with 264 patients, oral cryotherapy significantly decreased the incidence of OM (Relative Risk [RR]=0.46, 95% Confidence Interval [CI]=0.31~0.66), including severe OM (grade 2~4: RR=0.33, 95% CI=0.21~0.52; grade 3~4: RR=0.34, 95% CI, 0.22~0.53), and also reduced the OM severity score (Standardized Mean Difference [SMD]=−0.92, 95% CI=−1.25~−0.58). In addition, the need of intravenous narcotics therapy (RR=0.19, 95% CI=0.07~0.51) and the total parenteral nutrition (RR=0.54, 95% CI=0.35~0.84) were reduced. These results were associated with a significantly reduced length of hospitalization (Weighted Mean Difference [WMD]=−1.22, 95% CI=−2.37~−0.07).
CONCLUSION
Oral cryotherapy is effective and well-tolerated nursing intervention to alleviate OM among patients receiving myeloablative therapy before HSCT. Nurses caring for patients treated with myeloablative therapy should place high priority to prevent OM based on this evidence.

Citations

Citations to this article as recorded by  
  • Radyoterapiye Bağlı Oral Mukozit ve Yönetiminde Kanıta Dayalı Uygulamalar
    Ülkü Saygılı Düzova
    Black Sea Journal of Health Science.2025; 8(2): 79.     CrossRef
  • Nutritional interventions for the prevention and treatment of cancer therapy-induced oral mucositis: an umbrella review of systematic reviews and meta-analysis
    Reza Amiri Khosroshahi, Sepide Talebi, Sheida Zeraattalab-Motlagh, Hossein Imani, Amirabbas Rashidi, Nikolaj Travica, Hamed Mohammadi
    Nutrition Reviews.2023; 81(9): 1200.     CrossRef
  • Cryotherapy for oral mucositis in cancer: review of systematic reviews and meta-analysis
    Reza Amiri Khosroshahi, Sepide Talebi, Nikolaj Travica, Hamed Mohammadi
    BMJ Supportive & Palliative Care.2023; 13(e3): e570.     CrossRef
  • Oral cryotherapy for management of chemotherapy‐induced oral mucositis in haematopoietic cell transplantation: a systematic review
    Faizah Jabr Alsulami, Sadr ul Shaheed
    BMC Cancer.2022;[Epub]     CrossRef
  • Effectiveness of low level laser therapy versus cryotherapy in cancer patients with oral mucositis: Systematic review and network meta-analysis
    Chih-Chin Lai, Shiau-Yee Chen, Yu-Kang Tu, Yu-Wei Ding, Jiu-Jenq Lin
    Critical Reviews in Oncology/Hematology.2021; 160: 103276.     CrossRef
  • Kemoterapi ve Radyoterapi Alan Hastalarda Oral Mukozit: Bir Gözden Geçirme
    Seher ÇAKMAK, Nesrin NURAL
    Dokuz Eylül Üniversitesi Hemşirelik Fakültesi Elektronik Dergisi.2020; 13(3): 185.     CrossRef
  • Experiences of Unrelated Hematopoietic Stem-cell Donors and Experts of Relevant Institutions
    Soyoung Yu, Miok Kim, Tai-Gyu Kim, Su-Hee Beom
    Korean Journal of Adult Nursing.2019; 31(5): 522.     CrossRef
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  • 7 Crossref
  • 7 Scopus
Original Articles
PURPOSE
The purpose of study was to describe operation room nurses' ethical values in relationship to the attitude and meaning of life toward organ transplantation in brain death.
METHODS
This study used a descriptive correlational survey design. Participants were 174 nurses who had attended to organ transplantation surgery in brain death more than once. Data were collected from September 1 to 11, 2015 and were analyzed using independent t-test, ANOVA, Scheffé test, Pearson's correlation coefficients, and hierarchical multiple regression with SPSS 22.0.
RESULTS
Educational level, attitude on organ transplantation in brain death, and meaning of life were significant variables predicting the level of nursing ethical value, accounting for 82.6% of the variability.
CONCLUSION
Continued education and self-development programs should be encouraged for operating room nurses to establish professional nursing ethics as well as positive meaning of life and attitude toward the organ transplantation in brain death.

Citations

Citations to this article as recorded by  
  • Influencing Factors of Death Perception and Self-efficacy on Meaning in Life in Nurses who Experienced End of Life Care
    Hee Jung Hong, Sung Hee Choi, Bok Soon Shin
    The Korean Journal of Rehabilitation Nursing.2023; 26(1): 49.     CrossRef
  • Types of Perception toward Ethical Issues in Perioperative Nurses: Q-Methodological Approach
    Jin Nam Kim, Seok Hee Jeong
    Journal of Korean Academy of Nursing.2018; 48(6): 679.     CrossRef
  • Influence of Information Literacy and Perception of Patient Data Privacy on Ethical Values among Hospital Clinical Nurses
    Hyung-Eun Seo, Eun-Young Doo, Sujin Choi, Miyoung Kim
    Journal of Korean Academy of Nursing Administration.2017; 23(1): 52.     CrossRef
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  • 3 Crossref
  • 1 Scopus
Factors Influencing the Quality of Life in Families of Patients with Liver Transplantation
So Young Kim, Yun Mi Lee
Korean J Adult Nurs 2016;28(3):279-287.   Published online June 30, 2016
DOI: https://doi.org/10.7475/kjan.2016.28.3.279
PURPOSE
The purpose of this study was to identify factors influencing a family's quality of life (QoL) when one member has a liver transplantation.
METHODS
A total of 98 families were asked questions about characteristics, stress, social support and QoL. The instruments used for this study were the Stress Scale for Families of Liver Transplantation Recipients, the Personal Resources Questionnaire, the Korean version of QoL Simple Type Scale. Data were analyzed by t-test, ANOVA, Pearson's correlation coefficient and multiple regression.
RESULTS
The mean scores of stress was 2.58±0.75 and of social support was 4.81±0.87. The mean of the QoL was 3.39±0.60. Quality of life had significant correlations with stress and social support. Using multiple regression analysis, the QoL was significantly influenced by social support, stress and monthly average household income.
CONCLUSION
The results suggest that social support, stress and income should be considered in developing the nursing interventions to improve the QoL of families of patients with liver transplantation.

Citations

Citations to this article as recorded by  
  • The Caring Experience of Family Caregivers for Patients of Living Donor Liver Transplantation from the Family Members
    Miseon Bang, Suhye Kwon
    Journal of Korean Academy of Nursing.2022; 52(4): 435.     CrossRef
  • Impact of Self-esteem and Social support on Self-care Performance in Liver Transplantation Recipients
    Hyun Jung Jung, Young-Ju Kim
    The Korean Journal of Rehabilitation Nursing.2020; 23(2): 132.     CrossRef
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PURPOSE
This study aimed to examine the relationships among social support(family support, medical team support), hope, anxiety, and depression in patients with hematologic cancers before they received hematopoietic stem cell transplantation (HSCT) to obtain baseline data for developing a nursing intervention.
METHODS
The participants were 70 adult patients expecting to receive HSCT from 5 university hospitals in Seoul, Gyeonggi-do, and Jeollanam-do regions. A cross-sectional survey was done using standardized instruments for social support (Tae's Family Support Scale and Professional Medical Support Scale), hope (Kim & Lee Hope Scale), anxiety and depression (Hospital Anxiety and Depression Scale). The data were analyzed by SPSS/WIN 19.0 program using frequency, percentage, item mean and standard deviation, t-test, ANOVA, and Pearson's correlation coefficient.
RESULTS
Hope was significantly correlated with social support (r=.40, p=.001), anxiety (r=-.40, p<.001) and depression (r=-.58, p<.001). Anxiety was correlated with depression (r=.54, p<.001).
CONCLUSION
The findings of this study show greater social support for patients who expect to receive HSCT is significantly correlated to a higher level of hope, as well as low levels of anxiety and depression. In nursing practice, clinical nurses may develop a nursing intervention to reinforce social support and hope, as well as reduce anxiety and depression for patients preparing for HSCT.

Citations

Citations to this article as recorded by  
  • Relationship between perceived depression, suicidal ideation, and return to work among cancer survivors in South Korea: A national survey analysis
    Haeryun Cho, Hye Suk Jun
    Asia-Pacific Journal of Oncology Nursing.2025; 12: 100611.     CrossRef
  • Construção de protocolo de cuidados de enfermagem à criança no pós-transplante de células-tronco hematopoiéticas
    Jéssica Alline Pereira Rodrigues, Maria Ribeiro Lacerda, Cristina Maria Galvão, Ingrid Meireles Gomes, Marcia Regina Cubas, Ana Paula Pereira Fernandes
    Revista Gaúcha de Enfermagem.2022;[Epub]     CrossRef
  • Symptom Experience, Social Support, and Quality of Life in Patients with Hematologic Malignancies Undergoing Chemotherapy
    Ga Eun Kim, Ju-Eun Song, Mi-Ae You, Jin-Hee Park
    Asian Oncology Nursing.2022; 22(1): 29.     CrossRef
  • Construction of a nursing care protocol for children in post-hematopoietic stem cell transplantation
    Jéssica Alline Pereira Rodrigues, Maria Ribeiro Lacerda, Cristina Maria Galvão, Ingrid Meireles Gomes, Marcia Regina Cubas, Ana Paula Pereira Fernandes
    Revista Gaúcha de Enfermagem.2022;[Epub]     CrossRef
  • Experiences of Unrelated Hematopoietic Stem-cell Donors and Experts of Relevant Institutions
    Soyoung Yu, Miok Kim, Tai-Gyu Kim, Su-Hee Beom
    Korean Journal of Adult Nursing.2019; 31(5): 522.     CrossRef
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  • 5 Crossref
Experiences of Pregnancy and Childbirth in Women after Liver Transplantation
Hea Seon Ha, Kyung Choon Lim, Jung Ja Hong, In Ok Kim, Mi Kyeong Jeon, Jae Sim Jeong, Soon Haeng Lee, Haeng Mi Son, Myungsun Yi, Sung Gyu Lee
Korean J Adult Nurs 2013;25(6):690-700.   Published online December 31, 2013
DOI: https://doi.org/10.7475/kjan.2012.24.6.690
PURPOSE
Liver transplantation (LT) is the best treatment for patients with end-stage liver disease and most patients with LT return to their normal life. However, pregnancy and childbirth for women with LT are less common, mainly because it is considered to be dangerous for their health. The purpose of this study was to describe how Korean women after LT experience their pregnancy and childbirth.
METHODS
This study was designed to explore the experiences of pregnancy and childbirth of women with LT. Data were collected by individual in-depth interviews with four women who were pregnant and gave birth following LT in 2009. All interviews were audio-taped and transcribed verbatim. The transcribed data were analyzed using qualitative content analysis.
RESULTS
Four themes emerged as a result of analysis: recovery of lost feminity and marriage; fulfilling roles through pregnancy; life-risking pregnancy; and perfect family achieved by childbirth. These themes describe in detail about challenges and concerns the women with LT faced for their pregnancy and childbirth as well as many emotionally touching experiences.
CONCLUSION
The results of this study would support health professionals to be better prepared to help women with LT for pregnancy and childbirth by providing in-depth and insightful information.

Citations

Citations to this article as recorded by  
  • Lived Experiences of Korean Young Adults After Heart Transplantation: A Phenomenological Approach
    Hye Jin Yoo, Eunyoung E. Suh
    Asian Nursing Research.2021; 15(2): 89.     CrossRef
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  • 3 Scopus
Effects of Back Massage on Immune Response, Symptom Distress and Mood State of Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
Byung Eun Song, Yang Sook Yoo, Ok Hee Cho
J Korean Acad Adult Nurs 2009;21(3):269-280.   Published online June 30, 2009
PURPOSE
To examine the effect of back massage on immune response, symptom distress, and mood state of patients undergoing allogeneic hematopoietic stem cell transplantation (allogeneic HSCT).
METHODS
Subjects were thirty-seven patients undergoing sibling allogeneic HSCT (including 16 in the experimental group and 21 in the control group). Experimental subjects participated in an intervention group of back massage for 10 minutes, once a day and 5 times a week, from one week prior to the HSCT to the third week after the HSCT or a control group. A non-equivalent pretest-posttest design was used. t-test and Repeated measures ANOVA were used to examine group differences by using SAS.
RESULTS
No significant group differences were found in Immune response (CD4+, CD8+,CD19+, CD56+) and symptom distress. The experimental group had significantly less mood state (anxiety, confusion) than the control group.
CONCLUSION
The back massage for the patients undergoing allogeneic HSCT may be effective in altering the anxiety and confusion during hematopoietic stem cell transplantation. However, this study did not provide evidence in improving immune response and symptom distress.
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Analysis of Nursing Researches about Organ Donation and Transplantation in Korea
Hye Sook You, Hyang Sook So, Hye Sook Kim
J Korean Acad Adult Nurs 2008;20(6):895-904.   Published online December 31, 2008
PURPOSE
This study analyzes the trends of nursing researches about organ donation and transplantation, and recommends the direction of future nursing studies in Korea.
METHODS
Ninety-nine researches based upon organ donation and transplantation in Korea were analyzed by descriptive statistics.
RESULTS
Among them 58 papers were master's theses and 9 were doctoral dissertations. Articles about organ beneficiaries were seventy. The 47 articles among them were for kidney transplantation. By the types of research design, there were 73 quantitative studies, 19 qualitative studies, and 9 methodological studies. In correlation studies, the quality of life of subjects were evaluated the association with stress, social support, self-efficacy, and compliance. In experimental studies, the independent variables were self efficacy promotion exercise, steroid medication, educational programs regarding an organ transplantation and a brain death, Danjeon breathing exercise, and telephone counseling. The methods of qualitative studies were based on the grounded theory, phenomenology, interpretive phenomenology, and ethnography. The dominant concepts of qualitative researches were experiences of a decision-making of donors and of recipients for organ transplantation.
CONCLUSION
Descriptive surveys or correlation studies were predominant on the nursing research about organ transplantation. Qualitative studies were conducted to some extent. It is recommended to conduct clinically applicable interventional researches with the experimental design.
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Predictors of Quality of Life Following HSCT Recipients
Munju Jung, Haejung Lee
J Korean Acad Adult Nurs 2008;20(2):341-352.   Published online April 30, 2008
PURPOSE
The purpose of this study was to identify relatively important predictors of quality of life (QOL) of HSCT recipients among client's characteristics(age, gender, family income, religiosity), HSCT-related characteristics(time since HSCT, type of HSCT, decision maker of HSCT) and social support. METHODS: Eighty two participants who had a HSCT were recruited for the study. Data were analyzed by descriptive analysis, pearson's correlation, ANOVA and stepwise multiple regression using SPSS for Window(version 12.0) program to answer the research questions. RESULTS: Family income, time since HSCT and religiosity explained 23.8% of the variance in the QOL of HSCT recipients. HSCT recipients who had higher family income, longer time past since HSCT, and more religious tend to have higher quality of life. CONCLUSION: Based on the findings of this study, we could know that the HSCT recipients need certain amount of time to recover their QOL after HSCT. Opportunities of reemployment and religious support should be considered when we develop intervention program for HSCT recipients.
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Analysis of Nursing Interventions and Nursing Outcomes of the Patients with Liver Transplantation
Je Bog Yoo, Hee Jung Jang, Nam Cho Kim
J Korean Acad Adult Nurs 2003;15(4):509-519.   Published online December 31, 2003
PURPOSE
This study was designed to investigate the survey of analyzing nursing interventions and nursing outcomes of the patients with liver transplantation. METHOD: The subjects of this study consisted of 83 patients and fifteen nurses who took care of them. The methods of this study were retrospective and descriptive survey. RESULT: The mean age of patients was 42.7 years and the subjects were 62.7% males. 56.7% of these patients were diagnosed with liver cirrhosis of B type. The mean duration of hospitalization was 48.6 days. Ninety-five nursing interventions were performed at least daily. The most frequent used interventions were "environmental management: comfort", "medication administration: parenteral", "cough enhancement", and " oxygen therapy". Even though SGOT level to identify nursing outcomes was decreased, SGOT was not within normal limits. Therefore, even after discharge of patients, There is a need to take care of them carefully. CONCLUSION: Conclusion: These findings revealed the significance and need of nurse practitioners who performed professional nursing intervention for the patients with liver transplantation. Especially, it is necessary needs to develop the nursing intervention programs for comfort.
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The Change of Muscle Strength, Muscle Endurance, Flexibility and Activities of Daily Living of the Kidney Transplant Recipients
Jae Hyun Ahn, Hee Sun Ha, Jeong Ja Hong
J Korean Acad Adult Nurs 2001;13(1):5-14.   Published online March 31, 2001
The purpose of this study was to explore the change of muscle strength, muscle endurance, flexibility and activities of daily living to develop a rehabilitational program. The subjects were selected randomly among the patients who underwent kidney transplantations at one major transplantation hospital in Seoul, Korea. This study was carried out between November 23, 1999 and February 15, 2000. The subjects in this study consisted of 16 patients who had kidney transplantations between 1 month and 12 months ago prior to this study. They were all on steroids and did not take any physical exercise regularly. The muscle strength, muscle endurance, flexibility and activities of daily living were evaluated at 1st week and after 12 weeks. The data were analyzed with numbers, percentiles, mean, standard deviation and t-test. The results were as follows: 1. After 12 weeks, the grip strength was significantly decreased than 1st week (p=.0002). 2. After 12 weeks, the back lift strength was significantly decreased than 1st week (p=.0002). 3. After 12 weeks, the muscle endurance was increased than 1st week, but it was not significant(p=.5487). After 12 weeks, the flexibility was significantly decreased than 1st week (p=.0002). 5. After 12 weeks, the activities of daily living was significantly decreased than 1st week (p=.0006). Like the above result, the kidney transplant receipients' muscle strength, flexibility and activities of daily living were reduced. In order to solve this problem, the writer has found that program development to prevent the defects should be extremely required. Since now on the number of patients should expand. After the kidney transplantation, the periods of 4, 8, 12 and 16 weeks are extended. The writer proposes to examine the different phase of change in each periods.
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A Study on the Educational Needs of the Kidney Transplant Patients and Educational Importance perceived by Their Nurses
Jae Hyun Ahn
J Korean Acad Adult Nurs 2000;12(4):678-689.   Published online December 31, 2000
The purpose of this study was to explore the educational needs of kidney transplant patients and educational importance perceived by their nurses to develop a rehabilitational and educational program. Data were collected from January 29, 1999 to July 30, 1999 with interviews using a structured questionnaire. The subjects for this study were 173, of whom 107 were patients who had had a kidney transplant and had visited the out-patient department and 66 were transplant ward nurses who were taking care of the kidney transplant patients at six general hospitals located in Seoul. The questionnaire used for this study was developed by the investigator through a literature review and collected and modified by 11 professional personnel and 3 kidney transplant patients. The data were analyzed using the SAS program for numbers, percentiles, mean, standard deviation, t-test, ANOVA, and Scheff test. The results were as follows; 1) In the patient group, the total mean score for educational needs was 154.61 and the item mean score was 3.96. In the nurses group, the total mean score for perceived educational importance was 166.26 and the item mean score was 4.26. In the nurses group, perceived educational needs were scored higher than by the patient group. With regard to domains, both patient and nurses group had the highest educational needs and perceived educational importance in the domain of physical condition and the top five items in the educational needs and perceived educational importance were also in the domain of physical condition. 2) In the patient group, women and the divorce/bereavement group had higher educational needs in the domain of nutritional management, those who had been admitted longer than 4 weeks from their kidney transplant time had higher educational needs in the domains of physical condition and those who were less than 4 years from their transplant had higher educational needs in the domain of follow-up care. In the nurses group, those who were married had higher perceived educational importance in the domain of physical condition.
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The Analysis of the Family Function and Family Type of Kidney Transplant Recipients
Chung Ja Chun, Jeong Hyun Kim
J Korean Acad Adult Nurs 1999;11(4):796-808.   Published online December 31, 1999
The main purpose of this study was to characterize and classify families of KT recipients and to identify family adaptability and cohesion, as family function, by the Circumplex model. A Cross-sectional survey approach was employed for this research project. The data was collected by the questionnaire method in 3 general hospitals in Seoul and Kyonggi-do, Korea. The Family Adaptability and Cohesion Evaluation Scales III was used. By Convenient sampling, a total of 190 subjects (Male 117, Female 73) with an average age of 39.7 years (range: 18-62 yrs.) participated. The mean age at transplantation was 36.8 yrs. (SD: 9.4 yrs.). On an average, the patients had received transplants 39.9 months previously. The data was analyzed by percentage of frequency, t-test, and one-way ANOVA by the SPSS program. The results were as follows: 1. The mean family adaptability score was 30.26(SD: 6.6, range: 12-49) and the mean family cohesion score was 34.96(SD: 6.5, range: 15-48). 2. All of 16 distinct types of family system were identified. Among them, 'Flexibly connected types' (32 families, 16.8%) were the most common and 'chaotically disengaged types' (2 families, 1.1%) were the least common. 3. Dividing the 16 unit typology into 3 basic groups of types, 'Balanced types' composed 88 families (46.3%), 'Mid-range types' composed 76 families (40.0%), and 'extreme types' composed 26 families (13.7%). 4. The family adaptation differed according to age, education level, marital status, the diagnostic age of CRF, and level of recipient's perception of the family's importance. The family cohesion differed according to age, employment status, number of kid, and level of recipient's perception of the family's importance. In conclusion, by providing nursing intervention designed to increase family adaptability and cohesion, considering the socio-demographic factors of recipient and family, nurses may improve the recipient's family function and health, and also the recipient's health and quality of life.
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