PURPOSE The purpose of this study was to investigate the relationship among sleep quality, heart rate variability (HRV), fatigue, depression, and anxiety reported by Korean adults. METHODS A cross-sectional study of 208 adults aged 20~60 years was conducted using a short-term HRV analysis and self-reported questionnaires of Pittsburgh Sleep Quality Index (PSQI), Fatigue Severity Scale, Beck Depression Inventory, and State Trait Anxiety Inventory. RESULTS Subjects with good sleep quality (PSQI score≤5) had higher HRV total power (t=2.03, p=.043) and high-frequency (t=2.04, p=.043) with lower fatigue (t=−4.08, p < .001), depressive mood (t=−3.66, p < .001), and trait anxiety (t=−3.84, p < .001) than subjects with poor sleep quality. Poor sleep quality was negatively correlated with HRV total power (r=−.17, p=.016), high-frequency (r=−.14, p=.049), and positively fatigue (r=.39, p < .001), depression (r=.44, p < .001), state anxiety (r=.23, p=.001) and trait anxiety (r=.34, p < .001). CONCLUSION The results indicated that sleep quality is correlated with HRV which reflects the activities of the autonomic nerve system, fatigue, depression, and anxiety in adults.
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