Purpose This study aims to determine a hypothetical model concerning factors affecting hospital nurses’compliance with the guidelines of antineoplastic drugs safety management based on the theory of planned behavior. Methods Data were collected from 339 nurses managing antineoplastic drugs through an online survey conducted from March 23 to April 2, 2022. The data were analyzed using SPSS 28.0 and AMOS 25.0. Results The hypothetical model had the goodness of fit indices of χ2 =370.13 (df=140, p<.001), CFI=.94, SRMR=.07, and RMSEA=.07. Compliance with the guidelines was significantly influenced by compliance intention. Compliance intention and perceived behavioral controls’ explanatory power was 59.9% to explain compliance with the guidelines. In addition, compliance intention was significantly influenced by perceived behavioral control. Perceived behavioral control, attitude toward behavior, and subjective norm had an explanatory power of 65.2% to explain compliance intention. Moreover, perceived behavioral control was influenced by the knowledge of antineoplastic drugs safety management. Conclusion These findings suggest that for promoting hospital nurses’ compliance with the antineoplastic drugs safety management guidelines, an intervention strategy is required to enhance compliance intention, perceived behavior control, and antineoplastic drugs safety management knowledge.
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Purpose This descriptive survey study was conducted to determine the degree of implementation of anticancer drug safety management guidelines by nurses handling anticancer drugs, safety motivation, safety control, ward safety culture, and anticancer drug safety guidelines. Methods The subjects of this study were 136 nurses working in the designated ward for anticancer drug treatment, and data collection was conducted from November 3rd to November 16, 2021. Collected data were analyzed using the IBM SPSS statistics 28.0 program by frequency and percentage, mean and standard deviation, independent sample t-test, one-way ANOVA, Scheffé test, Pearson's correlation coefficients, and multiple regression analysis. Results As a result of analyzing the effects of the subjects’ knowledge of anticancer drug safety management guidelines, safety motivation, safety control, and ward safety culture on the implementation of anticancer drug safety guidelines, it was found to be knowledge of anticancer drug safety management guidelines (β=.22), with 7.0% of the explanatory power. Conclusion The factors influencing the implementation of anticancer drug safety management guidelines were found to be anticancer drug safety management guidelines, and it is suggested that follow-up studies be conducted to develop educational programs and interventions to improve anticancer drug safety guidelines.
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