PURPOSE
This study was conducted to identify the predictive factors for pre-diabetes in middle-aged Korean women based on the Korean National Health and Nutrition Examination Survey (KNHANES).
METHODS
In this cross-sectional study, data were extracted from the second year of the 6th KNHANES (2013~2015), conducted at 129 sites from January to December 2014. The 1,275 subjects were middle-aged women between 40 and 64 years of age characterized as “pre-diabetic” (n=618) or “normal” (n=657) according to the American Diabetes Association (ADA) standard. Multivariate binary logistic regression was used to determine factors influencing pre-diabetes in middle-aged women.
RESULTS
The significant factors for pre-diabetes were a Waist-to-Height Ratio (WHtR) > 0.53 (Odds Ratio [OR]=1.71, 95% Confidence Interval [CI]=1.27~2.29), increasing prevalence of hypercholesterolemia (OR=2.02, 95% CI=1.42~2.86), and low level of High-Density Lipoprotein (HDL) cholesterol (OR=1.89, 95% CI=1.18~3.02). In addition, as age increased after 50 years, the proportion of WHtR > 0.53 decreased in the normal group, but increased with age in the pre-diabetes group.
CONCLUSION
Education to raise awareness about diabetes including pre-diabetes is needed for effective management of hyperlipidemia and central obesity to ensure a healthy middle age.

Citations

• Predictors of Prediabetes Among Young Adults in East Java, Indonesia: A Cross-sectional Study
  Ika Nur Pratiwi, Ika Yuni Widyawati, Nursalam Nursalam, Zulfayandi Pawanis, Arina Qonaah, Bih O Lee
  Nurse Media Journal of Nursing.2024;[Epub]     CrossRef

PURPOSE
This study was conducted to identify the clinical characteristics and risk factors on the occurrence of variant angina, and to examine the predicting factors on the vascular endothelial dysfunction of the patients with variant angina.
METHODS
A total of 134 patients diagnosed with variant angina were recruited from 2006 to 2008. The degrees of endothelial dysfunction were measured and recorded by the researcher using the values of flow-mediated vasodilation of their brachial arteries and Nitroglycerine-mediated dilation. Subjects' demographic data and risk factors were gathered after obtaining informed consent, and their electronic medical records were reviewed to collect laboratory data.
RESULTS
The mean age was 54.2 +/- 9.6 years and 52% was male patients. More than 50% of the male patients were cigarette smokers and had hypercholesterolemia. 84% of the male patients and 70% of the female patients had more than one risk factor of cardiovascular disease. A stepwise multiple regression analysis showed that smoking and hypercholesterolemia predicted the decrease of flow-mediated vasodilation (Adjusted R(2) = .204, p < .001).
CONCLUSION
Tailored educational interventions for smoking cessation and cholesterol management are needed to prevent recurrence of angina attack for patients with variant angina and to prevent cardiovascular disease for middle-aged workers.