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"Hematopoietic stem cell transplantation"

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"Hematopoietic stem cell transplantation"

Original Articles
PURPOSE
This study aimed to examine the relationships among social support(family support, medical team support), hope, anxiety, and depression in patients with hematologic cancers before they received hematopoietic stem cell transplantation (HSCT) to obtain baseline data for developing a nursing intervention.
METHODS
The participants were 70 adult patients expecting to receive HSCT from 5 university hospitals in Seoul, Gyeonggi-do, and Jeollanam-do regions. A cross-sectional survey was done using standardized instruments for social support (Tae's Family Support Scale and Professional Medical Support Scale), hope (Kim & Lee Hope Scale), anxiety and depression (Hospital Anxiety and Depression Scale). The data were analyzed by SPSS/WIN 19.0 program using frequency, percentage, item mean and standard deviation, t-test, ANOVA, and Pearson's correlation coefficient.
RESULTS
Hope was significantly correlated with social support (r=.40, p=.001), anxiety (r=-.40, p<.001) and depression (r=-.58, p<.001). Anxiety was correlated with depression (r=.54, p<.001).
CONCLUSION
The findings of this study show greater social support for patients who expect to receive HSCT is significantly correlated to a higher level of hope, as well as low levels of anxiety and depression. In nursing practice, clinical nurses may develop a nursing intervention to reinforce social support and hope, as well as reduce anxiety and depression for patients preparing for HSCT.

Citations

Citations to this article as recorded by  
  • Relationship between perceived depression, suicidal ideation, and return to work among cancer survivors in South Korea: A national survey analysis
    Haeryun Cho, Hye Suk Jun
    Asia-Pacific Journal of Oncology Nursing.2025; 12: 100611.     CrossRef
  • Construção de protocolo de cuidados de enfermagem à criança no pós-transplante de células-tronco hematopoiéticas
    Jéssica Alline Pereira Rodrigues, Maria Ribeiro Lacerda, Cristina Maria Galvão, Ingrid Meireles Gomes, Marcia Regina Cubas, Ana Paula Pereira Fernandes
    Revista Gaúcha de Enfermagem.2022;[Epub]     CrossRef
  • Symptom Experience, Social Support, and Quality of Life in Patients with Hematologic Malignancies Undergoing Chemotherapy
    Ga Eun Kim, Ju-Eun Song, Mi-Ae You, Jin-Hee Park
    Asian Oncology Nursing.2022; 22(1): 29.     CrossRef
  • Construction of a nursing care protocol for children in post-hematopoietic stem cell transplantation
    Jéssica Alline Pereira Rodrigues, Maria Ribeiro Lacerda, Cristina Maria Galvão, Ingrid Meireles Gomes, Marcia Regina Cubas, Ana Paula Pereira Fernandes
    Revista Gaúcha de Enfermagem.2022;[Epub]     CrossRef
  • Experiences of Unrelated Hematopoietic Stem-cell Donors and Experts of Relevant Institutions
    Soyoung Yu, Miok Kim, Tai-Gyu Kim, Su-Hee Beom
    Korean Journal of Adult Nursing.2019; 31(5): 522.     CrossRef
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Effects of Back Massage on Immune Response, Symptom Distress and Mood State of Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
Byung Eun Song, Yang Sook Yoo, Ok Hee Cho
J Korean Acad Adult Nurs 2009;21(3):269-280.   Published online June 30, 2009
PURPOSE
To examine the effect of back massage on immune response, symptom distress, and mood state of patients undergoing allogeneic hematopoietic stem cell transplantation (allogeneic HSCT).
METHODS
Subjects were thirty-seven patients undergoing sibling allogeneic HSCT (including 16 in the experimental group and 21 in the control group). Experimental subjects participated in an intervention group of back massage for 10 minutes, once a day and 5 times a week, from one week prior to the HSCT to the third week after the HSCT or a control group. A non-equivalent pretest-posttest design was used. t-test and Repeated measures ANOVA were used to examine group differences by using SAS.
RESULTS
No significant group differences were found in Immune response (CD4+, CD8+,CD19+, CD56+) and symptom distress. The experimental group had significantly less mood state (anxiety, confusion) than the control group.
CONCLUSION
The back massage for the patients undergoing allogeneic HSCT may be effective in altering the anxiety and confusion during hematopoietic stem cell transplantation. However, this study did not provide evidence in improving immune response and symptom distress.
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Predictors of Quality of Life Following HSCT Recipients
Munju Jung, Haejung Lee
J Korean Acad Adult Nurs 2008;20(2):341-352.   Published online April 30, 2008
PURPOSE
The purpose of this study was to identify relatively important predictors of quality of life (QOL) of HSCT recipients among client's characteristics(age, gender, family income, religiosity), HSCT-related characteristics(time since HSCT, type of HSCT, decision maker of HSCT) and social support. METHODS: Eighty two participants who had a HSCT were recruited for the study. Data were analyzed by descriptive analysis, pearson's correlation, ANOVA and stepwise multiple regression using SPSS for Window(version 12.0) program to answer the research questions. RESULTS: Family income, time since HSCT and religiosity explained 23.8% of the variance in the QOL of HSCT recipients. HSCT recipients who had higher family income, longer time past since HSCT, and more religious tend to have higher quality of life. CONCLUSION: Based on the findings of this study, we could know that the HSCT recipients need certain amount of time to recover their QOL after HSCT. Opportunities of reemployment and religious support should be considered when we develop intervention program for HSCT recipients.
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